Using my v895 Europe maps, I just tried planning a route from Argaka on the west coast to Keryneia in the north of the "main bit" and it found a route ok,
I then tried Rizokarpaso (in the pointy bit to the far northeast) as the destination and it found a route for that too.
If you zoom in on the map are your start and end points on roads? Can you be more exact about your start and end points? Also how did you enter them? As addresses? City centres? Lat/Long coordinates?
With all these routing questions, the devil is in the detail....
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Finally, out of interest, in your planning preferences, is there a page for "Warn me when my route passes through an area with limited map information"?
I'd never really understood the point of that option, but it might be relevant in this situation.